Cynthia Rodriguez has filed divorce papers in Miami to end her nearly 6-year marriage to New York Yankees star Alex Rodriguez.

She alleged infidelity in her Miami-Dade County Family Court filing. She said Rodriguez has “emotionally abandoned his wife and children.”

“The marriage of the parties is irretrievably broken because of the Husband’s extra marital affairs and other marital misconduct,” it said in the divorce filing.

Cynthia’s lawyers cited Alex’s relationship with Madonna has the final straw in the failed marriage.

One of C-Rod’s lawyers, Maurice Kutner, told The Post last night that A-Rod’s “relationship with Madonna was the latest situation in a series of events” that doomed the marriage.

The lawyer said last year’s Stray-Rod incident with a buxom stripper, and now Madonna, have been traumatic for C-Rod.

“It’s huge, it’s devastating, it’s life-changing,” Kutner said. “It’s caused her tremendous stress, and she’s doing the best she can to deal with it.

Cynthia was rumored to be in France with rocker Lenny Kravitz over the weekend. Kravitz has denied the report.

It appears that A-Rod’s pocket book is about to take a big hit.  Thank goodness that he opted out and renogiated a long-term deal with the Bronx Bombers last winter.